Ideal Substrate for Cryo-Microscopy
3D reconstruction of rotavirus particles on Silicon Nitride 20 nm thick TEM Windows.
Representative image provided by Dr. Deb Kelly (Virginia Tech)
"Our initial findings indicate that viral particles prepared on Cryo-SiN, exhibited greater contrast in comparison to those prepared on holey carbon films under the same conditions. As a result, we were able to calculate 3D reconstructions of viral particles prepared on Cryo-SiN using a fraction of the images required for samples prepared on holey carbon films." Tanner et al. Microscopy & Microanalysis Abstract, 2013
- Avoid substrate degradation seen with carbon grids
- Plasma cleanable to reduce contaminants
- Our proprietary carbon coating may also improve charge dissipation leading to a reduction in beam induced movement
- Large 500 µm windows provide ~50 x 50 µm viewing from any orientation at 70 degrees of tilt for tomography
FEATURED TEM WINDOWS
